Detalhe da pesquisa
1.
Disruption of the Na+/K+-ATPase-purinergic P2X7 receptor complex in microglia promotes stress-induced anxiety.
Immunity
; 57(3): 495-512.e11, 2024 Mar 12.
Artigo
Inglês
| MEDLINE | ID: mdl-38395698
2.
Injured sensory neurons-derived galectin-3 contributes to neuropathic pain via programming microglia in the spinal dorsal horn.
Brain Behav Immun
; 117: 80-99, 2024 03.
Artigo
Inglês
| MEDLINE | ID: mdl-38190982
3.
OCP002, a Mixed Agonist of Opioid and Cannabinoid Receptors, Produces Potent Antinociception With Minimized Side Effects.
Anesth Analg
; 136(2): 373-386, 2023 02 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36638515
4.
Microglial Cannabinoid CB2 Receptors in Pain Modulation.
Int J Mol Sci
; 24(3)2023 Jan 25.
Artigo
Inglês
| MEDLINE | ID: mdl-36768668
5.
NOP01, a NOP receptor agonist, produced potent and peripherally restricted antinociception in a formalin-induced mouse orofacial pain model.
Neuropeptides
; 91: 102212, 2022 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-34826712
6.
OFP011 Cyclic Peptide as a Multifunctional Agonist for Opioid/Neuropeptide FF Receptors with Improved Blood-Brain Barrier Penetration.
ACS Chem Neurosci
; 13(21): 3078-3092, 2022 11 02.
Artigo
Inglês
| MEDLINE | ID: mdl-36262082
7.
Spinal endomorphins attenuate burn-injury pain in male mice by inhibiting p38 MAPK signaling pathway through the mu-opioid receptor.
Eur J Pharmacol
; 903: 174139, 2021 Jul 15.
Artigo
Inglês
| MEDLINE | ID: mdl-33933465
8.
Development of Multifunctional and Orally Active Cyclic Peptide Agonists of Opioid/Neuropeptide FF Receptors that Produce Potent, Long-Lasting, and Peripherally Restricted Antinociception with Diminished Side Effects.
J Med Chem
; 64(18): 13394-13409, 2021 09 23.
Artigo
Inglês
| MEDLINE | ID: mdl-34465090
9.
Synthesis and Biological Characterization of Cyclic Disulfide-Containing Peptide Analogs of the Multifunctional Opioid/Neuropeptide FF Receptor Agonists That Produce Long-Lasting and Nontolerant Antinociception.
J Med Chem
; 63(24): 15709-15725, 2020 12 24.
Artigo
Inglês
| MEDLINE | ID: mdl-33271020
10.
VF-13, a chimeric peptide of VD-hemopressin(α) and neuropeptide VF, produces potent antinociception with reduced cannabinoid-related side effects.
Neuropharmacology
; 175: 108178, 2020 09 15.
Artigo
Inglês
| MEDLINE | ID: mdl-32544481
11.
Spinal administration of the multi-functional opioid/neuropeptide FF agonist BN-9 produced potent antinociception without development of tolerance and opioid-induced hyperalgesia.
Eur J Pharmacol
; 880: 173169, 2020 Aug 05.
Artigo
Inglês
| MEDLINE | ID: mdl-32416184
12.
Central and peripheral modulation of gastrointestinal transit in mice by DN-9, a multifunctional opioid/NPFF receptor agonist.
Neurogastroenterol Motil
; 32(8): e13848, 2020 08.
Artigo
Inglês
| MEDLINE | ID: mdl-32281198
13.
Spinal DN-9, a Peptidic Multifunctional Opioid/Neuropeptide FF Agonist Produced Potent Nontolerance Forming Analgesia With Limited Side Effects.
J Pain
; 21(3-4): 477-493, 2020.
Artigo
Inglês
| MEDLINE | ID: mdl-31521796
14.
The multifunctional peptide DN-9 produced peripherally acting antinociception in inflammatory and neuropathic pain via µ- and κ-opioid receptors.
Br J Pharmacol
; 177(1): 93-109, 2020 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31444977
15.
Structural insight into the substrate recognition and transport mechanism of amino acid transporter complex ACE2-B0AT1 and ACE2-SIT1.
Cell Discov
; 9(1): 93, 2023 Sep 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37684251